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The study aimed to determine the feasibility and effectiveness of an introductory disease-specific educational program delivered during an acute exacerbation of COPD (AECOPD) on objective measures of disease-specific knowledge. Patients admitted to a community hospital with an AECOPD were randomly assigned to a control group (standard care) or intervention group (standard care + brief education). The intervention group received two 30-min education sessions in hospital or at home within 2 weeks of hospital admission. Feasibility measures included the number of eligible patients, compliance with the sessions, and number of follow-up measures completed. Disease-specific knowledge and informational needs were measured using the Bristol COPD Knowledge Questionnaire (BCKQ) and the Lung Information Needs Questionnaire (LINQ), respectively, before and after the intervention period. Thirty-one patients (mean age, 72 ± 10 years) with an AECOPD participated in the study. Of 102 approached patients, 75 consented to screening (73.5%) and 67 (66%) were eligible for the study. Thirty-four patients declined participation. All intervention patients (n = 15) completed the educational sessions and follow-up measures. Three patients (control group) did not complete the follow-up measures. The mean changes and SDs for the BCKQ in the intervention and control groups were 8 ± 5.14 and 3.4 ± 4.9, respectively (P = .02). No difference between groups was found for the LINQ (P = .80). A brief educational program delivered at the time of hospitalization for an AECOPD was feasible for a subset of patients, resulted in improved disease-specific knowledge, and may be a bridge to more active approaches. ClinicalTrials.gov; No.: NCT02321215; URL: www.clinicaltrials.gov.