Understanding the factors that control aging has been one of humanity's endless pursuits, from the mystical fountain of youth to practical healthful regimens to prolong life expectancy. A team of scientists at the University of California San Diego has helped decipher the dynamics that control how our cells age, and with it implications for extending human longevity. ...

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The structure of proteins that protect telomeres (shelterin proteins, from "protective shield") are promising targets to combat cancer, but to date, there has been no effective form for attacking them. In the absence of drugs that destroy telomeres, cancer retains one of its most terrible properties, which is the ability of its cells to divide perpetually. ...

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Multi-pronged approach reveals a delicate balance required for longevity Understanding the factors that control aging has been one of humanity’s endless pursuits, from the mystical fountain of youth to practical healthful regimens to prolong life expectancy. A team of scientists at the University of California San Diego has now helped decipher the dynamics that control how our cells age, and with it implications for extending human longevity. ...

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Humans have been searching for a cure for aging for as long as they have been capable of pondering their own mortality. In recent times, some scientists have even hinted that aging might not be a biological inevitability, that if we could identify the causes of aging, we might be able to stop it from happening or reverse it entirely. ...

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Dr. Jason Butler and his team discovered that aged blood vessels strongly influence the functional characteristics of blood stem cells. Transplantation of young blood vessel cells into older mice makes their aged stem cells take on the characteristics of young stem cells. ...

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Investigators at Case Western Reserve University School of Medicine and University Hospitals Health System have identified a new molecular pathway that controls lifespan and healthspan in worms and mammals. In a Nature Communications study published today, researchers showed that worms with excess levels of certain proteins lived longer and healthier than normal worms. ...

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The Salt Spring Foundation has offered the community a snapshot into its make-up and the unique factors shaping life on the island with the 2017 Salt Spring Island Vital Signs report. Released Tuesday afternoon, the much-anticipated report offers statistics on a wide range of data, from work and economy to arts and culture and the environment. ...

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Scientists may soon trial a new class of drugs that specifically aim to delay or treat ageing. Writing in the Journal of American Geriatrics this week, doctors from the Mayo Clinic and Scripps Research Institute outline a set of new clinical trial paradigms that could be used to test the efficacy and safety of “Senolytics”, a new class of drugs that target mechanisms in the ageing process. ...

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Many methods of modestly slowing aging in laboratory species are accompanied by reduced rates of protein synthesis and higher levels of activity by cellular maintenance processes such as autophagy. The research noted here is one of a number of examples from recent years in which an intervention lowers the rate of protein synthesis and slows aging as a result. ...

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A 2014 analysis by the Media Insight Project found that about 6 out of 10 Americans admit they did nothing more than scan the headlines in the past week. And that’s just the people that admit it. ...

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